PAIN

Interpreting recent findings on spinal pain

New research into the nature of spinal pain point to a complex bio-psycho-social relationship

Mr Kieran O'Sullivan, Chartered Physiotherapist, ISCP, Dublin

April 9, 2014

Article
Similar articles
  • Spinal pain is one of the most common reasons for patients to present in primary care.1 While spinal pain can be quite disabling in a small proportion of people, most people who develop it recover well and lead full, active lives.1

    Despite increasing expenditure, most spinal pain has no specific diagnosis2 and many common interventions have demonstrated little effectiveness.3,4,5,6,7 Typical clinical practice in recent decades may have in fact increased the disability associated with spinal pain,8 such that spinal pain has been labelled ‘a 20th century healthcare disaster’.9

    This article aims to use recent findings in spinal research to help address some key questions for primary care clinicians regarding spinal pain including:

    • What are the main risk factors for spinal pain?
    • How can we best identify, and assist, those patients most at risk of chronic, disabling spinal pain?

    What are the main risk factors for spinal pain?

    Biomechanical factors including prolonged occupational sitting,10 standing,11 lifting,12 manual handling,13 bending14 or twisting14 are no longer considered major risk factors for the development and maintenance of spinal pain. This is not to suggest such postures and activities are irrelevant in spinal pain, or that they are never associated with acute onset of spinal pain. Rather, it highlights that these postures and activities are actually performed as frequently in people without spinal pain. 

    Consistent with this, uni-dimensional ergonomic interventions aimed at improving the way in which such tasks are performed have minimal effectiveness.15 Similarly, many ‘pathologies’ observed on spinal imaging are equally common among people without spinal pain, and have little correlation with clinical findings.16

    In contrast, several other factors have been linked to people developing disabling spinal pain. These include a widespread distribution of pain,17 poor general health,18,19 depression,20 anxiety,21 chronic stress,22 acutely stressful traumatic events,23 fear,24 poor self-efficacy or coping,25 catastrophic thoughts,26 a pessimistic outlook on prognosis,27 a perceived danger of being physically active,28 reduced spinal range of motion,23 or excessively guarded or careful movement.29,30

    To summarise, the primary risk factors for chronic disabling spinal pain are not biomechanical or patho-anatomical in nature. Instead, the range of factors involved reflects the bio-psycho-social nature of spinal pain.31 It appears that the physiological effects of a range of psychosocial and cognitive factors abnormally sensitise the central nervous system, such that pain thresholds are lowered. This heightened sensitivity is compounded by unhelpful physical factors such as abnormal patterns of spinal movement. 

    Therefore, a mix of physical, lifestyle, psychosocial and cognitive factors interact in chronic spinal pain, and management strategies may need to address this. 

    Identifying, and assisting, those most at risk of chronicity

    Similar to any patient presentation, screening for the presence of any ‘red flag’ pathologies which may require specialist referral is essential.32 Thereafter, a detailed subjective history is critical, and provides greater insight than the physical examination. The established relationship between the primary care clinician and patient can also provide useful insights into the patient’s life. A guide to some issues worth considering in the assessment of spinal pain is provided in Table 1. In particular, determining if changes in any of these factors coincided with the onset of (or an increase in) spinal pain is very relevant.

    Relatively brief questionnaires,33,34 which cover issues such as those listed in Table 1 have been shown to be valid methods of identifying patients at risk of developing chronic, disabling spinal pain.

    This risk profiling approach can then be used to prioritise management strategies:

    • Low-risk patients report relatively localised pain, with low levels of distress, and little or no psychosocial factors. This group should be educated on the likely, positive prognosis for their spinal pain. They should be offered simple pain medications, and encouraged to return to their usual levels of physical activity
    • Moderate-risk patients report greater pain and distress, and some psychosocial risk factors are present. This group should receive the aforementioned education and advice, as well as conservative rehabilitation such as physiotherapy
    • High-risk patients report high levels of pain and distress, and several psychosocial risk factors are present. This group should receive the aforementioned education and advice, as well as conservative rehabilitation with a greater emphasis on addressing psychosocial obstacles to recovery.

    Primary care professionals can thus help prioritise the minority most at risk, while providing less costly, yet speedy and effective treatment for other patients. Some specific approaches which have been demonstrated to improve outcomes, and which are reflected in several clinical practice guidelines35,36 include:

    • Encourage patients to avoid bed rest, and to return to their usual levels of physical activity by reducing fears about the perceived safety of physical activity28,37
    • Provide simple analgesics to reduce pain in the short-term
    • Avoiding referral for spinal imaging unless considered medically required due to the presence of red flags, or at least delaying referral to allow time for natural recovery has been linked to reduced rates of surgery and disability16,38
    • If imaging is undertaken, assist patients to interpret the findings appropriately. Reassure patients that disc degeneration and other signs previously considered as ‘wear and tear’ are common among people without spinal pain, and have very little relationship to pain and disability. Avoid using technical language which implies significant pathology and spinal vulnerability as this increases patient fears39
    • In a minority of cases where a close correlation exists between the clinical presentation and specific pathology on spinal imaging, referral for surgical opinion may be worthwhile if conservative rehabilitation has been unsuccessful 
    • In addition, some simple physical examination procedures can help identify which specific spinal tissues, if any, are most closely related to the pain.40-43 However, in people with chronic spinal pain, such procedures are complicated by heightened tissue sensitivity, meaning they should only be considered in conjunction with the patient history
    • Avoid, and challenge, the perception that spinal pain usually reflects significant spinal damage. Reinforce the concept that spinal pain does not automatically suggest significant spinal damage, and instead reflects the sensitivity of the nervous system44
    • Similarly, reassure patients that perceptions of spinal subluxation,45 pelvic asymmetry,46 and other feared malalignments rarely, if ever, exist and are not linked to spinal pain
    • Reduce catastrophic thinking, and set specific, realistic rehabilitation goals26
    • Improve patient perceptions about the consequences of spinal pain, such that long-term disability is not seen as inevitable27
    • Empower patients to self-manage by improving their perception of their own ability to cope with pain, and their ability to participate in rehabilitation25
    • Encourage patients to restore normal range of movement, and normal patterns of movement in everyday tasks. This may involve referral for a specific exercise programme, or participation in a more comprehensive programme encompassing physical, psychosocial and cognitive contributors to their spinal pain.47

    Conclusion

    Spinal research challenges previously held beliefs about the close relationship between patho-anatomical changes and pain. Instead, psychosocial and cognitive factors, along with some physical factors such as guarded movement patterns, are more relevant predictors of chronicity. 

    Acute spinal pain usually resolves quickly, with early pain relief and restoration of physical activity linked to recovery and less recurrence. 

    Patients with chronic spinal pain may present with a mix of physical, psychosocial and cognitive issues which contribute to their pain. 

    The role of the primary care professional is to help patients return to full health by addressing whatever issues are relevant to their pain. This may include provision of pain relief, or addressing physical impairments such as changes in range of motion or muscle tone. It should, however also consider the role of psychosocial and cognitive factors in the patient’s pain. 

    This article outlines how using a simple risk stratification approach can help identify the mix of factors associated with an individual patient’s spinal pain. This reduces the likelihood of unnecessary, expensive and often unhelpful tests being performed. Such an approach not only reduces disability, but has also been shown to improve cost-effectiveness.38,48

    Through using such an approach in primary care, those most at risk of chronicity may be identified at an early stage, and suitable strategies implemented. This should lead to more positive outcomes for spinal pain than in recent decades.

     (click to enlarge)

    This article is published by the Irish Society of Chartered Physiotherapists (ISCP) in a booklet: Management of Spinal Joint Problems, a Physiotherapy Perspective. For a copy, contact the ISCP at Tel: 01 402 2148 or Email: info@iscp.ie. To find a chartered physiotherapist in your area see www.findaphysio.ie

    References 

    1. Woolf, A, et al. Burden of major musculoskeletal conditions. Bull World Health Organ, 2003;81:646-656.
    2. Borkan, J, et al. Advances in the field of low back pain in primary care: a report from the fourth international forum. Spine, 2002;27: E128-E132.
    3. Furlan, AD, et al. Acupuncture and dry-needling for low back pain: an updated systematic review within the framework of the Cochrane collaboration. Spine, 2005;30:944-963.
    4. Niemistö, L, et al. Radiofrequency denervation for neck and back pain: a systematic review within the framework of the cochrane collaboration back review group. Spine, 2003;28:1877-1888.
    5. Chou, R, et al. Surgery for low back pain: a review of the evidence for an American Pain Society clinical practice guideline. Spine, 2009;34:1094-1109.
    6. van Tulder, MW, et al. Outcome of invasive treatment modalities on back pain and sciatica: an evidence-based review. Eur Spine J, 2006;15:82-92.
    7. Furlan, AD, et al. Massage for low-back pain: a systematic review within the framework of the Cochrane Collaboration Back Review Group. Spine, 2002;27:1896-1910.
    8. Deyo, RA, et al. Overtreating chronic back pain: Time to back off? Journal of the American Board of Family Medicine, 2009;22:62-68.
    9. Waddell, G, The Back Pain Revolution. 2nd ed. 2004, Edinburgh: Churchill Livingstone.
    10. Roffey, D, et al. Causal assessment of occupational sitting and low back pain: results of a systematic review. Spine J, 2010;10:252-261.
    11. Roffey, D, et al. Causal assessment of occupational standing or walking and low back pain: results of a systematic review. Spine J, 2010;10:262-272.
    12. Wai, E, et al. Causal assessment of occupational lifting and low back pain: results of a systematic review. Spine J, 2010;10:554-566.
    13. Roffey, D, et al. Causal assessment of workplace manual handling or assisting patients and low back pain: results of a systematic review. Spine J, 2010;10:639-651.
    14. Wai, E, et al. Causal assessment of occupational bending or twisting and low back pain: results of a systematic review. Spine J, 2010;10:76-88.
    15. Driessen, MT, et al. The effectiveness of physical and organisational ergonomic interventions on low back pain and neck pain: a systematic review. Occup Environ Med, 2010;67:277-285.
    16. Chou, R, et al. Diagnostic imaging for low back pain: Advice for high-value health care from the American College of Physicians. Ann Intern Med, 2011;154:181-189.
    17. Smart, KM, et al. Mechanisms-based classifications of musculoskeletal pain: Part 1 of 3: Symptoms and signs of central sensitisation in patients with low back (±leg) pain. Man Ther, 2012;17:336-344.
    18. Ihlebaek, C, et al. Subjective health complaints in patients with chronic Whiplash Associated Disorders (WAD). Relationships with physical, psychological, and collision associated factors. Norwegian Journal of Epidemology, 2006;16:119-126.
    19. Tschudi-Madsen, H, et al. A strong association between non-musculoskeletal symptoms and musculoskeletal pain symptoms: results from a population study. BMC Musculoskelet Disord, 2011;12:285.
    20. Bair, MJ, et al. Depression and pain comorbidity: a literature review. Archives of Internal Medicine, 2003;163:2433-2445.
    21. McCracken, LM, et al. Pain-related anxiety predicts non-specific physical complaints in persons with chronic pain. Behaviour Research and Therapy, 1998;36:621-630.
    22. Blackburn-Munro, G, et al. Chronic pain, chronic stress and depression: coincidence or consequence? Journal of Neuroendocrinology, 2001;13:1009-1023.
    23. Sterling, M, et al. Physical and psychological factors maintain long-term predictive capacity post-whiplash injury. Pain, 2006;122:102-108.
    24. Crombez, G, et al. Pain-related fear is more disabling than pain itself: evidence on the role of pain-related fear in chronic back pain disability. Pain, 1999;80:329-339.
    25. Costa, LC, et al. Self-efficacy is more important than fear of movement in mediating the relationship between pain and disability in chronic low back pain. Eur J Pain, 2011;15:213-219.
    26. Sullivan, M, et al. A psychosocial risk factor-targeted intervention for the prevention of chronic pain and disability following whiplash injury. Phys Ther, 2006;86:8-18.
    27. Buchbinder, R, et al. Population based intervention to change back pain beliefs and disability: three part evaluation. BMJ, 2001;322:1516-1520.
    28. Vlaeyen, JWS, et al. The treatment of fear of movement/(re) injury in chronic low back pain: further evidence on the effectiveness of exposure in vivo. Clin J Pain, 2002;18:251.
    29. Sullivan, M, et al. Psychological influences on repetition-induced summation of activity-related pain in patients with chronic low back pain. Pain, 2009;141:70-78.
    30. Dankaerts, W, et al. Discriminating healthy controls and two clinical subgroups of nonspecific chronic low back pain patients using trunk muscle activation and lumbosacral kinematics of postures and movements: A statistical classification model. Spine, 2009;34:1610-1618.
    31. Smart, KM, et al. The discriminative validity of “nociceptive,” “peripheral neuropathic,” and “central sensitization” as mechanisms-based classifications of musculoskeletal pain. Clin J Pain, 2011;27:655-663.
    32. Greenhalgh, S, et al., Red flags: A guide to identifying serious pathology of the spine. 2006, London: Churchill Livingstone.
    33. Hill, JC, et al. Comparing the STarT back screening tool’s subgroup allocation of individual patients with that of independent clinical experts. Clin J Pain, 2010;26:783-787.
    34. Hockings, RL, et al. A systematic review of the predictive ability of the Orebro Musculoskeletal Pain Questionnaire. Spine, 2008;33:E494-E500.
    35. Koes, B, et al. Clinical guidelines for the management of low back pain in primary care: an international comparison. Spine, 2001;26:2504-2514.
    36. Savigny, P, et al. Early management of persistent non-specific low back pain: summary of NICE guidance. BMJ, 2009;338:
    37. Maher, C, et al. Prescription of activity for low back pain: what works? AJP, 1999;45:121-132.
    38. Webster, BS, et al. Relationship of early magnetic resonance imaging for work-related acute low back pain with disability and medical utilization outcomes. J Occup Environ Med, 2010;52:900-907.
    39. Sloan, TJ, et al. Explanatory and Diagnostic Labels and Perceived Prognosis in Chronic Low Back Pain. Spine, 2010;35:E1120-E1125.
    40. May, S, et al. Centralization and directional preference: A systematic review. Man Ther, 2012;In Press:
    41. Laslett, M, et al. Diagnosis of sacroiliac joint pain: validity of individual provocation tests and composites of tests. Man Ther, 2005;10:207-218.
    42. Jull, G, et al. The accuracy of manual diagnosis for cervical zygapophyseal joint pain syndromes. Medical Journal of Australia, 1988;148:233-236.
    43. Nice, DA, et al. Intertester reliability of judgments of the presence of trigger points in patients with low back pain. Arch Phys Med Rehab, 1992;73:893-898.
    44. Moseley, L. Combined physiotherapy and education is efficacious for chronic low back pain. AJP, 2002;48:297-302.
    45. Mirtz, TA, et al. An epidemiological examination of the subluxation construct using Hill’s criteria of causation. Chiropractic & Osteopathy, 2009;17:13.
    46. Levangie, PK. The association between static pelvic asymmetry and low back pain. Spine, 1999;24:1234-1242.
    47. Fersum, K, et al. Efficacy of classification based cognitive functional therapy in patients with non-specific chronic low back pain – A randomized controlled trial. Eur J Pain, 2013;17:916-928.
    48. Hill, JC, et al. Comparison of stratified primary care management for low back pain with current best practice (STarT Back): a randomised controlled trial. Lancet, 2011;378:1560-71. 
    © Medmedia Publications/Forum, Journal of the ICGP 2014